Impact of coronary physiological assessment for myocardial blood flow and resistance in patients with dilated cardiomyopathy

Impact of coronary physiological assessment for myocardial blood flow and resistance in patients with dilated cardiomyopathy - COMBO-DCM study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000039988

Enrollment

Registered

2020-04-01

Start date

2020-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dilated cardiomyopathy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Left ventricular dysfunction and dilation (ejection fraction <40% and left ventricular end-diastolic diameter >56mm[male]/>50mm[female] in echocardiography) 2) Indication of cardiac catheterization and coronary physiological assessment

Exclusion criteria

Exclusion criteria: 1) Previous history of admission for heart failure 2) Diagnosis of secondary cardiomyopathy 3) Under transvenous catecholamine injection, cardiac resynchronization therapy or ventricular assist device at cardiac catheterization 4) Coronary stenosis =or>90% 5) Atrial fibrillation at cardiac catheterization 6) Bronchial asthma 7) Severe valvular disease

Design outcomes

Primary

Measure	Time frame
Change in left ventricular ejection fraction between baseline and 12 months after coronary physiological assessment	—

Secondary

Measure	Time frame
All-cause mortality, cardiac death, admission for heart failure, cardiac resynchronization therapy, ventricular assist device, heart transplantation	—

Countries

Japan

Contacts

Public ContactTaishi Yonetsu

Tokyo Medical and Dental University Cardiovascular medicine

t-yonetsu.cvm@tmd.ac.jp03-5803-5231

Outcome results