Intraoperative dexmedetomidine as an adjuvant to general anesthesia improves postoperative analgesia and quality of recovery.

Intraoperative dexmedetomidine as an adjuvant to general anesthesia improves postoperative analgesia and quality of recovery. - Intraoperative dexmedetomidine as an adjuvant to general anesthesia improves postoperative analgesia and quality of recovery.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039944

Enrollment

Registered

2020-06-01

Start date

2020-10-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia

Interventions

Dexmedetomidine as an analgesic/Saline Intraoperative administration only for about 4 hours 0.5 mcg /kg / hr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: General anesthesia without epidural anesthesia

Exclusion criteria

Exclusion criteria: Patients with reduced cardiac function (low cardiac output, advanced valvular disease, advanced atrioventricular block), patients with reduced circulating blood volume, severe anemia, liver dysfunction, renal dysfunction, drug dependence, extubation in the operating room after surgery

Design outcomes

Primary

Measure	Time frame
Demonstrating that dexmedetomidine improves postoperative analgesia and quality of recovery on the 1st day after surgery using NRS scale and QoR40 score.	—

Countries

Japan

Contacts

Public ContactHiroshi Yamashita

Kobe city medical center general hospital department of anesthesiology

cantateveritas@kcho.jp0783024321

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026