Head and neck cancer
Conditions
Interventions
Conduct exercise therapy intervention 5 times a week for 7 weeks. Exercise therapy includes stretching, resistance training, endurance training. Provide nutritional support for foods containing 6 g of
Sponsors
Niigata University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Head and neck cancer patients diagnosed by histology or cytology who undergo chemoradiotherapy with cisplatin as first-line treatment. Patients with written informed consent has been obtained. Patients who can receive the regimen of cisplatin 80mg /m2 every 3 weeks. ECOG Performance status is 0, 1 or 2. Patients with sufficient liver, kidney and bone marrow functions are maintained. Patients with white blood cell count 3,000 / mm3 or more, platelet count 100000 /mm3 or more, less than twice the AST facility standard upper limit, less than twice the ALT facility standard upper limit, eGFR 40 ml / min or more.
Exclusion criteria
Exclusion criteria: Patients not for curative treatment. Patients with pacemaker implantation. Patients with chemoradiotherapy after induction chemotherapy. Patients with chemoradiotherapy as adjuvant therapy. Patients determined by the attending physician to be inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of skeletal muscle mass | — |
Secondary
| Measure | Time frame |
|---|---|
| Chemoradiotherapy completion rate, adverse events, PG-SGA, Clinical biochemistry and hematology, motor function evaluation | — |
Countries
Japan
Contacts
Public ContactRyusuke Shodo
Niigata University Department of Otorhinolaryngology, Head and Neck Surgery
Outcome results
None listed