Estimation of intracerebral concentrations of poisonous drugs using human iPS-derived brain microvascular endothelial cells

Estimation of intracerebral concentrations of poisonous drugs using human iPS-derived brain microvascular endothelial cells - Estimation of intracerebral concentrations of poisonous drugs using human iPS-derived brain microvascular endothelial cells

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000039870

Enrollment

500

Registered

2020-03-18

Start date

2020-03-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug intoxication

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Residual samples of the previous study (UMIN000035447), in which the subjects meet the following criteria. 1.Patients who visited the Advanced Critical Care and Emergency Center in Teikyo University Hospital (including emergency patients) 2.Patients suspected of poisoning, which is written in the medical record. 3.Patient who collected blood or urine for treatment.

Exclusion criteria

Exclusion criteria: 1.Patients or family of whom expressed an intention to refuse to participate in this study. 2.Patients whose residual specimens are inadequate for this study. 3.Those who are judged inappropriate by the investigators.

Design outcomes

Primary

Measure	Time frame
Intracerebral free drug concentration estimated from drug concentration in plasma of patients	—

Countries

Japan

Contacts

Public ContactHiroyuki Hosono

Teikyo University Hospital Center for Clinical Research & Trial

hhosono@med.teikyo-u.ac.jp03-3964-1211

Outcome results