The study of the effects of intellectual disability and oral antiepileptic drugs on awaking from general anesthesia

The study of the effects of intellectual disability and oral antiepileptic drugs on emergence from total intravenous anesthesia - The effects of intellectual disability and antiepileptic drugs on emergence from total intravenous anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000039855

Enrollment

Registered

2020-04-01

Start date

2020-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental patients undergoing total intravenous anesthesia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)BMI is less than 30, 2)ASA is PS 1 or 2, 3)Anesthesia time will be less than 5 hours, 4)Patients undergoing dental treatment or minor oral surgery, 5)No need receiving opioid analgesics for postoperative analgesia

Exclusion criteria

Exclusion criteria: 1)Patients with contraindications for propofol, remifentanil, rocuronium, 2)Patients who are judged to be inappropriate for study participation

Design outcomes

Primary

Measure	Time frame
1)Blood concentration of propofol at the discontinuation of propofol and tracheal extubation, 2)Time from the discontinuation of propofol to tracheal extubation and 3)BIS value at tracheal extubation	—

Secondary

Measure	Time frame
1)Propofol amount and average infusion rate of propofol, 2)Estimated blood concentration of propofol at the discontinuation of propofol and tracheal extubation, 3)Remifentanil amount and average infusion rate of remifentanil, 4)BIS values before & during anesthesia, and at the discontinuation of propofol.	—

Countries

Japan

Contacts

Public ContactHitoshi Higuchi

Okayama University Hospital Department of Dental Anesthesiology

higuti@md.okayama-u.ac.jp086-235-6721

Outcome results