Impact of left ventricular stiffness by diastolic wall strain on atrial high rate episodes after pacemaker implantation

Impact of left ventricular stiffness by diastolic wall strain on atrial high rate episodes after pacemaker implantation - LEADER study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000039790

Enrollment

100

Registered

2020-05-12

Start date

2020-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients scheduled for pacemaker implantation without a history of atrial fibrillation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients scheduled for pacemaker implantation without a history of atrial fibrillation

Exclusion criteria

Exclusion criteria: Excludes patients with organic heart disease (cardiomyopathy, history of myocardial infarction, severe valvular disease), cardiac surgery, hemodialysis, and pacing-dependent.

Design outcomes

Primary

Measure	Time frame
One year atrial tachycardia episode after pacemaker implantation	—

Secondary

Measure	Time frame
(Before implanting a pacemaker) Clinical data: age, gender, medical history, arrhythmia type, comorbid heart disease, past history, medications, height, weight, NYHA classification, Blood sampling: Cre, Hb, UA, BNP, proBNP, Troponin-T ECG: heart rate, QRS wave form, presence or absence of leg block, Trans thoracic echocardiography: Left atrial diameter, left atrial volume, left ventricular wall thickness, LV mass index, left ventricular end diastolic diameter, left ventricular systolic diameter, left ventricular ejection fraction, E wave, deceleration time, E / e` ratio, diastolic wall strain (Pacemaker implantation technique) Pacemaker type, setting, lead position (right atrial appendage, right ventricular apex, other) (After pacemaker implantation) Atrial hypertachycardia episode (atrial rate of 180 / min or more lasting for 6 minutes or more) at 1 month, 3 months, and 6 months after pacemaker visit.	—

Measure

Time frame

(Before implanting a pacemaker) Clinical data: age, gender, medical history, arrhythmia type, comorbid heart disease, past history, medications, height, weight, NYHA classification, Blood sampling: Cre, Hb, UA, BNP, proBNP, Troponin-T ECG: heart rate, QRS wave form, presence or absence of leg block, Trans thoracic echocardiography: Left atrial diameter, left atrial volume, left ventricular wall thickness, LV mass index, left ventricular end diastolic diameter, left ventricular systolic diameter, left ventricular ejection fraction, E wave, deceleration time, E / e` ratio, diastolic wall strain (Pacemaker implantation technique) Pacemaker type, setting, lead position (right atrial appendage, right ventricular apex, other) (After pacemaker implantation) Atrial hypertachycardia episode (atrial rate of 180 / min or more lasting for 6 minutes or more) at 1 month, 3 months, and 6 months after pacemaker visit.

—

Countries

Japan

Contacts

Public ContactTakanao Mine

Hyogo College of Medicine Department of Cardiovascular and Renal Medicine

mine@hyo-med.ac.jp81-798-45-6553

Outcome results