Effect of Low Level Laser Therapy on Wound Healing and Levels of Osteoprotegerin (OPG) In Gingival crevicular fluid following Open Flap Debridement: A Randomized Controlled Clinical Trial

Effect of Low Level Laser Therapy on Wound Healing and Levels of Osteoprotegerin (OPG) In Gingival crevicular fluid following Open Flap Debridement: A Randomized Controlled Clinical Trial - Effect of Low Level Laser Therapy on Wound Healing and Levels of Osteoprotegerin (OPG) In Gingival crevicular fluid following Open Flap Debridement: A Randomized Controlled Clinical Trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039770

Enrollment

Registered

2020-03-12

Start date

2017-12-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

Arm 1: Open flap debridement with Low level laser therapy at baseline, 3 months and 6 months 0.8-1.2 watt for 3 cycles/10 seconds duration: 3 cycles/10 seconds each cycle arm 2: Open flap debridemen

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with chronic periodontitis presence of atleast 20 permanent teeth clinical probing depth more than or equal to 5 mm and less than 8 mm post phase 1 therapy

Exclusion criteria

Exclusion criteria: pregnant and lactating women patient allergic to medications patient with systemic disease smokers

Design outcomes

Primary

Measure	Time frame
Decrease in clinical parameters following low level laser therapy and more increase in osteoprotegerin levels on laser treated site	—

Countries

Asia(except Japan)

Contacts

Public ContactShivjot Chhina

ITS Dental College Greater Noida

hod.perio.gn@its.edu.in9811787808

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026