Changes in heart rate caused by nitrous oxide during general anesthesia

Changes in heart rate caused by nitrous oxide during general anesthesia - Changes in heart rate caused by nitrous oxide

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039750

Enrollment

Registered

2020-03-10

Start date

2020-03-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who undergo general anesthesia

Interventions

Intervention group is administrated nitrous oxide for 15 minutes in each case. FiO2 is 0.3. Control group is administrated air mixed oxygen for 15 minutes in each case. FiO2 is 0.3. If the heart rat

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who undergo general anesthesia using inhalational anesthetics combined epidural anesthesia 2. Supine position, 3. ASA-PS1,2 4. Intubated cuffed tracheal tube 5. scheduled urological operation of over 150 minutes

Exclusion criteria

Exclusion criteria: 1. Past history of cardiac,respiratory,or neuromuscular disease affecting respiratory function 2. Upper respiratory infection 3. non-scheduled operation 4. allergy of anesthetics

Design outcomes

Primary

Measure	Time frame
Change in the heart rate from the control	—

Countries

Japan

Contacts

Public ContactKei Nakai

Miyagi Children's Hospital Clinical Research Center

kei.nakai@miyagi-children.or.jp0223915111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026