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Characterization of tau neuropathology of late-life psychiatric disorders: A PET study with 18F-PM-PBB3

Characterization of tau neuropathology of late-life psychiatric disorders: A PET study with 18F-PM-PBB3 - Characterization of tau neuropathology of late-life psychiatric disorders: A PET study with 18F-PM-PBB3

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000039740
Enrollment
75
Registered
2020-03-10
Start date
2020-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Late-life psychiatric disorders

Interventions

PET with 18F-PMPBB3 / Neuropsychological tests PET with 18F-PMPBB3 / Neuropsychological tests

Sponsors

National Institute of Radiological Sciences (NIRS) National Institutes for Quantum and Radiological
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: I. Patients 40 y.o.<=Age patients with late-life psychiatric disorders II. Healthy volunteers 20 y.o.<=Age normal subjects

Exclusion criteria

Exclusion criteria: I. Patients 1. Subjects with a severe physical complication 2. Subjects with metallic medical device in the body 3. Subjects with severe claustrophobia 4. Subjects who tends to suicide 5. Pregnant women 6. Subjects who is considered to be inappropriate to participate in the study II. Healthy volunteers 1. Subjects with any psychiatric disorder 2. Subjects with any organic brain disorder 3. Subjects with severe physical complication 4. Subjects with metallic medical device in the body 5. Subjects with tattoo 6. Subjects with severe claustrophobia 7. Pregnant women 8. Subjects who has participated in other study in recent 6 months. 9. Subjects who is considered to be inappropriate to participate in the study

Design outcomes

Primary

MeasureTime frame
Topology and quantification of 18F-PMPBB3 accumulation in the brain of patients with late-life psychiatric disorders and healthy subjects.

Countries

Japan

Contacts

Public ContactKeisuke Takahata

National Institute of Radiological Sciences (NIRS) National Institutes for Quantum and Radiological Department of Functional Brain Imaging Research

takahata.keisuke@qst.go.jp0432063251

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026