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Single facility prospective study on fertility-preserving treatment by cryopreservation of ovarian tissue and autologous ovarian tissue transplantation for CAYA generation patients on the premise of treatment likely to abolish gonad function

Single facility prospective study on fertility-preserving treatment by cryopreservation of ovarian tissue and autologous ovarian tissue transplantation for CAYA generation patients on the premise of treatment likely to abolish gonad function - CAYA ovary cryopreservation study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000039717
Enrollment
70
Registered
2020-03-05
Start date
2020-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. Hematopoietic malignancy (Hodgkin&#39

Interventions

Sponsors

Mie University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1) Patients aged between 3 and 40 years old at the time of cryopreservation of ovarian tissue and between 18 and 45 years old at the time of ovarian tissue transplantation (transplantation over 45 years is not recomended by the guidelines of the Japanese Society of Reproductive Medicine) 2) Hematopoietic malignancies (Hodgkin's lymphoma, etc.), cervical cancer (squamous cell carcinoma), breast cancer, rare cancers other than hematopoietic malignancies, blood diseases requiring hematopoietic cell transplantation (aplastic anemia, etc.) or autoimmunity Patient diagnosed with the disease 3) Patients judged by the attending physician to have a potential remission of the underlying disease 4) Patients with Performance Status (PS; criteria for establishing the Eastern Cooperative Oncology Group (ECOG)) of 0-1 5) Patients who have been fully informed of the contents of this study using the prescribed consent document and other explanatory documents, and who voluntarily agree to participate in this study in writing Patients who have been obtained) 6) Patients who can undergo ovariectomy within 2 weeks after explanation and consent

Exclusion criteria

Exclusion criteria: 1) Patients with a high probability of metastasis of the original disease to the ovary 2) Patients with obvious infections 3) Patients with severe uncontrollable complications 4) Patients whose doctor judges that this study is inappropriate for participation

Design outcomes

Primary

MeasureTime frame
Birth rate in cryopreserved ovarian tissue autotransplant population

Countries

Japan

Contacts

Public ContactTadashi Maezawa

Mie University Department of Obstetrics and Gynecology, Mie univercity hospital

mie-oncofertility@clin.medic.mie-u.ac.jp059-232-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026