The efficacy of a combination of exercise and duloxetine on physical disability in patients with non-specific chronic low back pain

The efficacy of a combination of exercise and duloxetine on physical disability in patients with non-specific chronic low back pain - The efficacy of a combination of exercise and duloxetine on physical disability in patients with non-specific chronic low back pain

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039713

Enrollment

Registered

2020-03-06

Start date

2017-02-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-specific chronic low back pain

Interventions

A comobination of supervised physical exercise and duloxetine administration. exercise: Patients were required to attend the program(tunk muscle stretching and strengthening) at outpatients rehabilit

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with non-specific chronic low back pain of at least 3 months' duration.

Exclusion criteria

Exclusion criteria: Malalignment of the lumbar spine, spondylolysis, spondylolisthesis, disc herniation, infection, spinal compression fracture, and tumor. Furthermore,exclusion criteria included a history of previous lumbar spine surgery; severe cardiovascular, hepatic, or renal disorders; pregnancy; gait disturbance requiring crutches or a walker; any type of treatment for LBP within 1 month before the first visit; and psychogenic disorders.

Design outcomes

Primary

Measure	Time frame
Roland-Morris Disability Questionnaire (RDQ) Timepoints: baseline and 15 weeks after intervention	—

Secondary

Measure	Time frame
Numerical rationg scale (NRS), Pain catastrophizing scale (PCS), Hospital anxiety and depression scale (HADS) Timepoints: baseline and 15 weeks after intervention	—

Countries

Japan

Contacts

Public ContactToru Mashimo

Zenshukai Hospital Department ofn Urology

k-saito@zenshukai.com027-261-5410

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026