Novel Ultrasonographic Scoring System of Sinusoidal Obstruction Syndrome associated with Oxaliplatin-based Chemotherapy in patients with Gastrointestinal Cancer.

Novel Ultrasonographic Scoring System of Sinusoidal Obstruction Syndrome associated with Oxaliplatin-based Chemotherapy in patients with Gastrointestinal Cancer. - Novel Ultrasonographic Scoring System of Sinusoidal Obstruction Syndrome associated with Oxaliplatin-based Chemotherapy in patients with Gastrointestinal Cancer.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000039697

Enrollment

Registered

2020-03-05

Start date

2019-12-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal cancer treated with oxaliplatin-based chemotherapy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients with gastrointestinal cancer who are planned to receive scheduled to receive oxaliplatin-based chemotherapy.

Exclusion criteria

Exclusion criteria: 1) Patients who have received Oxaliplatin in past treatment. 2) Patients with cirrhosis or chronic hepatitis. 3) Case after liver resection. 4) Case after splenectomy.

Design outcomes

Primary

Measure	Time frame
The primary endpoint is a probability that a high score of HokUS-10 and the increases in spleen volume of computed tomography are observed in the same case.	—

Secondary

Measure	Time frame
The secondary endpoint is a probability that a high score of HokUS-10 and the diagnosis of SOS/VOD based on histopathological findings are observed in the same case.	—

Countries

Japan

Contacts

Public ContactRika Saito

Hokkaido University Hospital Division of Cancer Center

lica.saitou@med.hokudai.ac.jp0117161161

Outcome results