Require dental procedure under intravenous sedation
Conditions
Interventions
Sedation with dexmedetomidine and propofol
Sedation with dexmedetomidine and midazolam
Sponsors
Osaka University Graduate School of Dentistry
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Require dental procedure under intravenous sedation 2. From 20 to 65 years of age 3. American Society of Anesthesiologists (ASA) physical status 1 or 2
Exclusion criteria
Exclusion criteria: 1. A history of allergic reactions to the drugs used in this study 2. Allergic reaction to yolk and soy 3. Hepatic or renal dysfunction 4. Maternal and nursing women 5. Circulatory or respiratory dysfunction 6. Acute narrow-angle glaucoma 7. Myasthenia gravis 8. Receiving HIV protease inhibitors or HIV reverse transcriptase inhibitors 9. Prescribed antipsychotics 10. brain disorder 11. Severe obesity, micrognathia, tonsillar hypertrophy, sleep apnea syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time from the end of the sedatives administration until the Romberg test is successfully performed. | — |
Secondary
| Measure | Time frame |
|---|---|
| Time from the end of the sedatives administration until achieving an Aldrete score of 9 or 10. Time from the end of the sedatives administration until patients possible to sit. Time from the end of the sedatives administration until patients possible to stand up. | — |
Countries
Japan
Contacts
Public ContactHiroshi Hanamoto
Department of Dental Anesthesiology 1-8, Yamadaoka, suita, Osaka, Japan
Outcome results
None listed