Relationship between ocular blood flow and structure-function in glaucoma patients.

Relationship between ocular blood flow and structure-function in glaucoma patients. - Relationship between ocular blood flow and structure-function in glaucoma patients.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039667

Enrollment

308

Registered

2020-06-01

Start date

2020-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open angle glaucoma

Interventions

Mydriasis for LSFG imaging

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients with glaucoma who did not meet exclusion criteria.

Exclusion criteria

Exclusion criteria: 1. visual acuity is less than 0.5. 2. refractive error is outside of +/- 6 diopter and cylinder is outside of +/- 2 diopter. 3. Axial length is more than 26.5mm. 4. Participants who have corneal opacity or cataract with Grade III of Emery-Little criteria. 5. False positive, falde negative, and fixation loss is more than 30%. 6. Participants who have experienced ocular surgery except for cataract (include multi fourcal IOL). 7. Participants who have experienced refractive surgery. 8. Participants who have experienced retinal, vitreous and choroidal disease, 9. Participants who have experienced cardiovascular condition or diabetes. 10. Systolic blood pressure at rest is more than 150mmHg or diastolic blood pressure at rest is more than 90mmHg. 11. Participants who have medicines related to ocular blood flow such as calcium blocker, alpha-1 blocker, beta-1 blocker, and PDE5 inhibitor agent. 12. Participants who have allergy for pupil dilation drops. 13. Participants who don't response to pupil dilation drops.

Design outcomes

Primary

Measure	Time frame
To determine the feature of ocular blood flow among healthy subjects, primary open angle glaucoma, normal tension glaucoma patients.	—

Secondary

Measure	Time frame
To compare patients backgrounds (age, gender, blood pressure, visual acuity, corneal curve, reflation, axial length, intra-ocular pressure, visual field sensitivity, perfusion density, retinal nerve fiber thickness, ganglion cell layer thickness, BMI, family history, smoking history) among healthy subjects, primary open angle glaucoma, normal tension glaucoma patients.	—

Countries

Japan

Contacts

Public ContactKazunori Hirasawa

Kitasato University School of medicine Department of Ophthalmology

hirasawa@kitasato-u.ac.jp0427788464

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026