Coordinated strain and Response of Contraction by Left Bundle Branch Pacing Study

Prospective evaluation of efficacy of left bundle branch pacing in patients with bradycardia - CORRECT-LBB Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000039647

Enrollment

Registered

2020-05-01

Start date

2020-03-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bradycardia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Among patients referred to Sapporo City General Hospital for permanent pacemaker implantation due to bradycardia, (1) those with a LVEF greater than 35% and left bundle branch block, (2) those with failure of His bundle pacing, are eligible. (3) Patients undergoing implantation of a cardiac resynchronization therapy (CRT) device, with lack of appropriate coronary sinus vein for a LV lead placement, are also eligible.

Exclusion criteria

Exclusion criteria: Patients who are judged as inappropriate for the study by investigators are excluded.

Design outcomes

Primary

Measure	Time frame
Changes in maximum rate of left ventricular pressure (LV-dP/dtmax) and 2D-speckle tracking strain of left ventricle by left bundle branch pacing	—

Secondary

Measure	Time frame
1 All-cause death, heart failure hospitalization, upgrade to biventricular pacing 2 Reoperation, lead dislodgement, device infection 3 Relationship between LV-dp/dtmax and optimal AV delay 4 Echographic changes of LV strain, LVEF, and LVDd 5 Change in NT-proBNP	—

Countries

Japan

Contacts

Public ContactToba Masahiro

Sapporo City General Hospital Cardiovascular Medicine

masahiro-toba@doc.city.sapporo.jp011-726-2211

Outcome results