chronic constipation
Conditions
Interventions
None listed
Sponsors
Nihon University School of Medicine, Division of Gastroenterology and Hepatology, Department of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: When two or more of the following symptoms persist for 3 months or more a) less than 3 spontaneous bowels per week b) More than 25% of the stools are active c) Rabbit stool or hard stool is present in at least 25% of the bowel movement d) 25% or more of bowel movements have a feeling of residual stool d) Over 25% of bowel movements have rectal anal obstruction e) More than 25% of defecations have manual defecation promotion measures
Exclusion criteria
Exclusion criteria: (1) Intestinal obstruction due to tumor, hernia, etc. is confirmed or suspected. (2) When taking digoxin or dabigatran etexilate methanesulfonate (since these effects may be enhanced when used in combination) (3) Patients who did not agree to participate in this clinical trial (4) Those who are judged to be inappropriate as subjects by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relationship between effective and non-effective cases of erobixibat and patient background factors (age, gender, frequency of bile acid transporter expression in terminal ileum, SNP type) | — |
Countries
Japan
Contacts
Public ContactChika Kusano
Nihon University School of Medicine Division of Gastroenterology and Hepatology, Department of Medicine
Outcome results
None listed