Parkinson'
Conditions
Interventions
None listed
Sponsors
National Hospital Organization Osaka Toneyama Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: At the beginning of the observation period, patients who satisfy all of the following conditions are included. 1) The consent has been obtained from the participant himself / herself through the explanatory document and consent form 2) Age at the time of obtaining consent is 20 years or older and less than 85 years. Both men and women. 3) Parkinson's disease patients with H & Y I or higher.
Exclusion criteria
Exclusion criteria: 1) Patients with drug addiction / alcoholism 2) Patients with severe physical symptoms other than Parkinson's disease (heart, liver, renal dysfunction, hematopoietic disorders, etc.) 3) Patients with severe mental symptoms (confusion, hallucinations, delusions, abnormal behavior, etc.) within 3 months before obtaining consent form 4) Other patients who are judged inappropriate to participate in the study by the attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Age, gender, wake-up time/ meal time/ bedtime, activity, sleep status, name of medicine, disease duration, Sleep questionnaire (ESS, RBD score, PDSS-2), hair follicle (clock gene expression levels (Period1, Period2, Period3, Cryptochrome1, Cryptochrome2, Bmal1, Npas2, Nr1d1, Nr1d2, DBP, DEC1, DEC2, etc.)) | — |
Countries
Japan
Contacts
Public ContactTakuyuki Endo
National Hospital Organization Osaka Toneyama Medical Center Department of Neurology
Outcome results
None listed