Objective evaluation by functional near-infrared spectroscopy(fNIRS) of the relationship between color tone and photophobia in patients with the eye diseases.

Objective evaluation by functional near-infrared spectroscopy(fNIRS) of the relationship between color tone and photophobia in patients with the eye diseases. - Objective evaluation of photophobia.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039532

Enrollment

Registered

2020-03-01

Start date

2013-04-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retinal degeneration group (including retinitis pigmentosa), eyelid and facial muscle spasm group (including hemifacial spasm and blepharospasm), ocular surface disorder group (including dry eye), and nerve atrophy group (including advanced glaucoma).

Interventions

Frontal lobe activation measurement using fNIRS (functional near-infrared spectroscopy) under four conditions with 1000 lx light load for 1.5 minutes.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Retinal degeneration group (including retinitis pigmentosa), eyelid and facial muscle spasm group (including hemifacial spasm and blepharospasm), ocular surface disorder group (including dry eye), and nerve atrophy group (including advanced glaucoma) with photophobia.

Exclusion criteria

Exclusion criteria: Unstable medical condition Unmeasurable Eyelid opening impossible in light load of 1000 lx Expected of phototoxic Obvious misalignment of the eyes If you think researchers unsuitable

Design outcomes

Primary

Measure	Time frame
Objective quantitative evaluation of photophobia.	—

Secondary

Measure	Time frame
Determination of photophobia reduce color by each disease.	—

Countries

Japan

Contacts

Public ContactMasafumi Ono

Nippon Medical School Department of Ophthalmology

ono@nms.ac.jp03-3822-2131

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026