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An epigenetic analysis and gene expression profiling on autoimmune gastritis; a multicenter cross-sectional and prospective study

An epigenetic analysis and gene expression profiling on autoimmune gastritis; a multicenter cross-sectional and prospective study - An epigenetic analysis and gene expression profiling on autoimmune gastritis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000039528
Enrollment
50
Registered
2020-03-01
Start date
2020-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

autoimmune gastritis

Interventions

None listed

Sponsors

Graduate School of Medicine, The University of Tokyo, Center for Epidemiology and Preventive Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Case with confirmed diagnosis of AIG 2) Case with confirmed diagnosis of active HP infection 3) Case without chronic gastritis by endoscopy and inapplicable to 1),2)

Exclusion criteria

Exclusion criteria: -Cases with medical history of H. pylori eradication treatment -Cases with regular use of proton pomp inhibitor (PPI) / potassium-competitive acid blocker (P- CAB) -Cases with medical history of surgical operation of the upper digestive tract -Cases with medical history of malignant disease (last 5 years, with the exception of intramucosal cancer cured by local treatment) -Patients with hereditary gastrointestinal tumor diseases (familial adenomatous polyposis, Lynch syndrome, hereditary nonpolyposis colorectal cancer, Peutz-Jeghers syndrome, Cowden syndrome, hereditary diffuse gastric cancer etc.) -Cases with use of 2 or more antiplatelet drugs or anticoagulants, or with coagulation abnormalities -Cases with regular use of steroids -Minor/elderly person/handicapped person who require special consideration

Design outcomes

Primary

MeasureTime frame
Gene expression profiling and epigenetic analysis

Secondary

MeasureTime frame
Statistical analysis associated with the risk of neoplasm emergence

Countries

Japan

Contacts

Public ContactKeiko Niimi

Graduate School of Medicine, The University of Tokyo Center for Epidemiology and Preventive Medicine

k-niimi@umin.ac.jp03-3815-5411

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026