Establishment of ultrasound-guided harvest of synovium for regenerative medicine of cartilage and meniscus using synovial mesenchymal stem cells

Establishment of ultrasound-guided harvest of synovium for regenerative medicine of cartilage and meniscus using synovial mesenchymal stem cells - Establishment of ultrasound-guided harvest of synovium

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039516

Enrollment

Registered

2020-02-18

Start date

2020-09-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Ultrasound-guided harvest of synovium in the knee joint

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Knee osteoarthritis patients who have total knee arthroplasty in our hospital and agree with the research

Exclusion criteria

Exclusion criteria: Patients who are in bad general condition Patients who have an infectious disease Patients who are judged as unappropriate in this research

Design outcomes

Primary

Measure	Time frame
Evaluation of safety 1. Neurovascular injury just after the surgery 2. Infection Evaluation of synovial mesenchymal stem cells 1. Proliferation 2. Differentiation potential 3. Cell surface marker Adverse event	—

Countries

Japan

Contacts

Public ContactNobutake Ozeki

Tokyo Medical and Dental University Center for Stem Cell and Regenerative Medicine

ozeki.arm@tmd.ac.jp03-5803-4017

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026