Effects of combined consumption of catechins and chlorogenic acids on postprandial glucose, insulin, incretin response and insulin sensitivity in healthy men: a randomized, double-blind, placebo-controlled crossover trial

Effects of combined consumption of catechins and chlorogenic acids on postprandial glucose, insulin, incretin response and insulin sensitivity in healthy men: a randomized, double-blind, placebo-controlled crossover trial - Effects of combined consumption of catechins and chlorogenic acids [n2016003]

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039514

Enrollment

Registered

2020-02-29

Start date

2016-09-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Control food 3 weeks consumption &gt

wash out 2 weeks &gt

test food 3 weeks consumption Test food 3 weeks consumption &gt

control food 3 weeks consumption

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: (1) Age >= 20 and < 60years (2) Subjects who have given written informed consent prior to start of study

Exclusion criteria

Exclusion criteria: (1) Subjects having diabetes (2) Subjects who have a history or signs of a heart or cerebrovascular disease (3) Subjects having diabetes, a liver, kidney or respiratory disease, endocrine disorder, metabolic disorder, organ disorder, gout, rheumatism, autoimmune disease, allergy disease, mental disorder, cancer, infection disease, or other diseases (4) Subjects who take an antidiabetic drug or antihyperlipidemic drug (5) Subjects having thyroid deficiency (6) Subjects who have a smoking habit (7) Heavy drinker (8) Subjects who have donated over 200 mL of blood within the last one month prior to the current study or over 400 mL of blood within the last three months prior to the study (9) Subjects who have severe anemia (Hb <=7 g/dL) (10) Subjects who have allergic reaction to food (11) Subjects who are judged to be inappropriate for the study by the medical doctor or investigator for other reason

Design outcomes

Primary

Measure	Time frame
Blood glucose	—

Secondary

Measure	Time frame
Insulin, GLP-1, GIP, HOMA-R, Matsuda Index	—

Countries

Japan

Contacts

Public ContactAya Yanagimoto

Kao Corporation Biological Science Research laboratories

yanagimoto.aya@kao.com03-5630-7476

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026