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Antibacterial effect of oral spray containing L8020 lactic acid bacteria against oral bacteria

Exploratory study on the effects of oral spray containing Lactobacillus rhamnosus L8020 in the oral cavity (compared with tablets containing L8020) - Exploratory study on the effects of oral spray containing L8020

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000039503
Enrollment
50
Registered
2020-02-25
Start date
2020-02-25
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy person

Interventions

Oral spray administration (60 minutes) Tablet administration (60 minutes)

Sponsors

Hiroshima University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Teachers / staff working at Hiroshima University or students attending Hiroshima University 1. Those who are older than 20 years old and older than 70 years old when obtaining consent 2. Person who can obtain consent from the person in writing regarding participation in this research

Exclusion criteria

Exclusion criteria: 1. Those who have dairy allergy 2. Those who have dental illnesses that require dental treatment 3. Persons with diseases that affect bad breath outside the oral cavity (Sjogren's syndrome, sinusitis, other systemic diseases, etc.) 4. Those who have taken L8020-containing products within 3 weeks before registration 5. Participants in other clinical research (including clinical trials) 6. Those who are deemed inappropriate by the person in charge of conducting the research 7. Those who have an interest in the researcher

Design outcomes

Primary

MeasureTime frame
Bad breath (by bad breath measuring instrument)

Secondary

MeasureTime frame
Caries risk (by using a simple saliva test kit) Periodontal disease status (with a simple saliva test kit) Taste, fragrance, residual feeling (questionnaire survey)

Countries

Japan

Contacts

Public ContactTsuyoshi Taji

Hiroshima University Department of Oral Biology & Engineering, Graduate School of Biomedical & Health Sciences

taji@hiroshima-u.ac.jp082-257-5622

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026