Usefulness of laminin gamma 2 (LG2m) as predictive factor for the development of hepatocellular carcinoma

Usefulness of laminin gamma 2 (LG2m) as predictive factor for the development of hepatocellular carcinoma - Usefulness of laminin gamma 2 (LG2m) as predictive factor for the development of hepatocellular carcinoma

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000039467

Enrollment

5800

Registered

2020-02-12

Start date

2020-02-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with risk factors for hepatocellular carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients Cohort 1: previously diagnosed as chronic hepatitis C and achieved sustained virological responses Cohort 1: currently diagnosed as chronic hepatitis B and receive nucleos (t) ide analogues Cohort 3: diagnosed as alcoholic liver injury Cohort 4: diagnosed as diabetes mellitus and over 50 years of age Cohort 5: diagnosed as fatty liver and over 50 years of age 2) having no history of hepatocellular carcinoma 3) age at entry is Cohort1,2,3: 20 years or older and younger than 90 years Cohort4,5: 50 years or older and younger than 90 years 4) Cohort1: obtaining sustained viral response by direct-acting antiviral agent Cohort2: receiving nucleos(t)ide analogue and suppressing HBV-DNA under 3.0 LogIU/mL Cohort3: consuming alcohol of 60g or more

Exclusion criteria

Exclusion criteria: 1) hepatocellular carcinoma 2) acute hepatitis 3) decompensated liver cirrhosis 4) having an active malignancy 5) serious complications 6) having an infection (except for viral hepatitis) 7) having a psychiatric disorder or psychiatric symptom 8) inappropriate for participant of this study

Design outcomes

Primary

Measure	Time frame
incidence of hepatocellular carcinoma	—

Countries

Japan

Contacts

Public ContactTakeshi Terashima

Kanazawa University Hospital Department of Gastroenterology

tera20jp@gmail.com076-265-2235

Outcome results