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End-tidal carbon dioxide (ETCO2) monitoring during Non-invasive ventilation

Accuracy evaluation of Main Stream and Side Stream End-Tidal CO2 Monitoring during Non-Invasive positive pressure Ventilation: A randomized crossover trial - MASCAT-NIV trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000039459
Enrollment
60
Registered
2020-02-28
Start date
2020-03-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients who are planed for NPPV to prevent respiratory failure after extubation

Interventions

Inner cup via mask (main stream) group measurement of ETCO2 using NPPV cap-ONE mask set(Nihon Kohden), CO2 censor kit
TG-980 (Nihon Kohden) Nasal prong and oral scoop (side stream) group measurement of ETCO2 using Smart CapnoLine H Plus O2 (Oridion medical)

Sponsors

JA Hiroshima General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patients undergoing mechanical ventilation, planed for NPPV after extubation, are screened. The patients who pass Spontaneous Breathing Trial (SBT) , the difference between ETCO2 and PaCO2 5 mmHg or less during SBT, and an arterial line is placed.

Exclusion criteria

Exclusion criteria: indication for intubation (GCS 8 or less, inability to protect airway, hemodynamic instability, severe hypoxemia) agitation, intolerance for NPPV obstructive pulmonary disease diagnosed pulmonary embolism, or suspected severe anemia (Hb < 7.0 g/dL) not to correct blood gas sample difficult to include decided by physician not to get consent

Design outcomes

Primary

MeasureTime frame
correlation and agreement between ETCO2 and PaCO2 measured by a main stream monitoring using an NPPV cap-ONE mask set and a side stream monitoring using nasal prong and oral scoop

Countries

Japan

Contacts

Public ContactMasaaki Sakuraya

JA Hiroshima General Hospital Department of Emergency and Intensive Care medicine

sakuraya-hma@umin.ac.jp+81-829-36-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026