sarcopenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients in hospital or outpatient of hospital of Kyoto Prefectural University of Medicine, or a person who participated in the Uzumasa physical fitness measurement at Kyoto University of Advanced Science 2.Patients who consent to study participation with the document by free will 3.Patients aged 65 and over at the time of consent acquisition 4.Gender does not matter [Sarcopenia group:10 people] 1) The lower leg circumference is below the sarcopenia screening standard value by AWGS (Asian Working Group for Sarcopenia) 2019 cut-off value: male<34cm, female<33cm 2)Those who meet the sarcopenia diagnostic criteria by AWGS 2019 (sarcopenia, severe sarcopenia; A+B, A+C, or A+B+C) A. Low skeletal muscle mass evaluated by Bioelectrical Impedance Analysis cut-off value:male<7.0kg/m2, female<5.7kg/m2 B. Low muscle strength evaluated by grip power cut-off value:male<28kg, female<18kg C. Low physical function evaluated by walking speed cut-off value<1.0m/s [Non-sarcopenia group:10 people] Those who do not meet the above criteria
Exclusion criteria
Exclusion criteria: 1. Pregnant woman 2. Inappropriate MRI imaging for the following reasons Pacemaker user History of cerebral artery clipping Use non-MRI compatiblemetal implants in the body Use of metal implant in lower leg Tattoo and art makeup Claustrophobia 3. Those who have difficulty assessing motor function for the following reasons History of myocardial infarction, symptomatic angina or arrhythmias. Uncontrolled tachycardia Uncontrolled hypertension Symptomatic lung disease High risk of fracture Infectious disese 4. Others. The person whom the doctor judged inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The diffusion tensor imaging parameter of skeletal muscle | — |
Secondary
| Measure | Time frame |
|---|---|
| SARC-F (Questionnaire) Lower leg circumference Grip power Lower limb muscle strength Physical ability (walking speed,timed-up-and-go test (TUG) , Chair rise test) Balance ability (Functional reach test, Standing on single leg) Body composition | — |
Countries
Japan
Contacts
Graduate School of Medical Science, Kyoto Prefectural University of Medicine Department of Rehabilitation Medicine