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Evaluation of the skeletal muscle function using diffusion tensor imaging

Study on the depiction of skeletal muscle function of sarcopenia using diffusion tensor imaging - Evaluation of the skeletal muscle using diffusion tensor imaging

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000039447
Enrollment
20
Registered
2020-03-01
Start date
2020-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sarcopenia

Interventions

Evaluation of physical function and body composition, and MRI imaging are performed for the sarcopenia group. Evaluation of physical function and body composition, and MRI imaging are performed for

Sponsors

Department of Rehabilitation Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients in hospital or outpatient of hospital of Kyoto Prefectural University of Medicine, or a person who participated in the Uzumasa physical fitness measurement at Kyoto University of Advanced Science 2.Patients who consent to study participation with the document by free will 3.Patients aged 65 and over at the time of consent acquisition 4.Gender does not matter [Sarcopenia group:10 people] 1) The lower leg circumference is below the sarcopenia screening standard value by AWGS (Asian Working Group for Sarcopenia) 2019 cut-off value: male<34cm, female<33cm 2)Those who meet the sarcopenia diagnostic criteria by AWGS 2019 (sarcopenia, severe sarcopenia; A+B, A+C, or A+B+C) A. Low skeletal muscle mass evaluated by Bioelectrical Impedance Analysis cut-off value:male<7.0kg/m2, female<5.7kg/m2 B. Low muscle strength evaluated by grip power cut-off value:male<28kg, female<18kg C. Low physical function evaluated by walking speed cut-off value<1.0m/s [Non-sarcopenia group:10 people] Those who do not meet the above criteria

Exclusion criteria

Exclusion criteria: 1. Pregnant woman 2. Inappropriate MRI imaging for the following reasons Pacemaker user History of cerebral artery clipping Use non-MRI compatiblemetal implants in the body Use of metal implant in lower leg Tattoo and art makeup Claustrophobia 3. Those who have difficulty assessing motor function for the following reasons History of myocardial infarction, symptomatic angina or arrhythmias. Uncontrolled tachycardia Uncontrolled hypertension Symptomatic lung disease High risk of fracture Infectious disese 4. Others. The person whom the doctor judged inappropriate

Design outcomes

Primary

MeasureTime frame
The diffusion tensor imaging parameter of skeletal muscle

Secondary

MeasureTime frame
SARC-F (Questionnaire) Lower leg circumference Grip power Lower limb muscle strength Physical ability (walking speed,timed-up-and-go test (TUG) , Chair rise test) Balance ability (Functional reach test, Standing on single leg) Body composition

Countries

Japan

Contacts

Public ContactSuzuyo 0hashi

Graduate School of Medical Science, Kyoto Prefectural University of Medicine Department of Rehabilitation Medicine

reha@koto.kpu-m.ac.jp075-251-5324

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026