Investigation of the occult-bacterial translocation induced by surgical stress

Investigation of the occult-bacterial translocation induced by surgical stress - O-BT induced by surgical stress

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039440

Enrollment

300

Registered

2020-03-01

Start date

2020-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing highly invasive abdominal surgery.

Interventions

Collect fecal sample before surgery. Collect blood sample immediately after the induction of general anesthesia and after the completion of surgery.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are going to undergo highly invasive abdominal surgery as the followings: * Major hepatectomy (with and without extrahepatic bile duct resection) * Pancreatoduodenectomy * Hepatopancreatoduodenectomy * Distal pancreatectomy with celiac axis resection * Subtotal esophagectomy * Other surgeries, which are considered highly invasive by the primary investigator

Exclusion criteria

Exclusion criteria: * Patients who reject participation for this study

Design outcomes

Primary

Measure	Time frame
The incidence of occult-bacterial translocation induced by surgical stress and its impact on postoperative course.	—

Secondary

Measure	Time frame
The association of the preoperative intestinal microenvironment and the incidence of occult-bacterial translocation.	—

Countries

Japan

Contacts

Public ContactYukihiro Yokoyama

Nagoya University Graduate School of Medicine Department of Surgery, Division of Surgical Oncology

yyoko@med.nagoya-u.ac.jp0527442222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026