The Accuracy of saline-induced FFR(sFFR) instead of fractional flow reserve(FFR) to evaluate the severity of coronary stenosis.

The Accuracy of saline-induced FFR(sFFR) instead of fractional flow reserve(FFR) to evaluate the severity of coronary stenosis. - The correlation between sFFR and FFR

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039397

Enrollment

300

Registered

2020-02-05

Start date

2019-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary stenosis

Interventions

Adding sailne-induce FFR during coronary angiography with FFR &amp

SFR

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Primary registration Patients with coronary angiography for coronary stenosis Secondary registration 1 Patients with coronary artery disease who undergo coronary angiography and judged having stenosis with 50% or more by 2 interventionists (at least one of them including specialists in Japanese Association of Cardiovascular Intervention and Therapeutics) 2 no particular limitation of the lesion site (left anterior descending artery, left circumflex branch, right coronary artery), history of PCI, and lesion form (in stent restenosis, calcified lesion) 3 over 20 years old 4 patients obtained document consents by the patient's will with sufficient understanding after receiving sufficient explanation for the participation of this study

Exclusion criteria

Exclusion criteria: 1) Patients with severe valvular disease 2) Patients with decompensated heart failure 3) Patients with extreme bradycardia (HR <40 or less) 4) Patients who can not use Adenosine necessary for FFR 5) Patients with co-morbidities such as acute liver injury and renal disorder that have serious effects on life 6) coronary total occlusion 7) Patients who are judged inappropriate for participation in this study by the responsible doctor

Design outcomes

Primary

Measure	Time frame
The accuracy of saline-induced FFR	—

Countries

Japan

Contacts

Public ContactHiroyuki Kiriyama

The University of Tokyo Hospital Cardiovascular Medicine

kiriyaman0427@gmail.com03-3815-5411

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026