A Non-Randomized, Open-Label Retrospective Cohort Study to Examine the Efficacy of 3D Power Doppler and VOCAL Test in Hormone Replacement Cycle Frozen-Thawed Embryo Transfer

A Non-Randomized, Open-Label Retrospective Cohort Study to Examine the Efficacy of 3D Power Doppler and VOCAL Test in Hormone Replacement Cycle Frozen-Thawed Embryo Transfer - A Non-Randomized, Open-Label Retrospective Cohort Study to Examine the Efficacy of 3D Power Doppler and VOCAL Test in Hormone Replacement Cycle Frozen-Thawed Embryo Transfer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039218

Enrollment

180

Registered

2020-01-21

Start date

2018-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

Endometrial 3D US-PDA assessed by VOCAL software (Plane C and 15-degree rotation step) Transvaginal ultrasound for endometrial thickness

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: *infertile patients undergoing a frozen-thawed embryo transfer (hormonal replacement) cycle at our institution *both husband and wife are nonsmokers

Exclusion criteria

Exclusion criteria: *male infertility *uterine malformation *Uterine fibroids and adenomyosis with luminal deformities *history of cesarean section *chocolate cysts > 3 cm in diameter *marital chromosomal abnormality *More than two miscarriage *antiphospholipid antibody syndrome

Design outcomes

Primary

Measure	Time frame
Comparison of the AUC of the ROC curve between the conventional model and the new model when the objective variable is live birth acquisition.	—

Secondary

Measure	Time frame
Comparison of AUCs when the objective variable is implantation and clinical pregnancy.	—

Countries

Japan

Contacts

Public ContactShinnosuke Komiya

HORAC Grand Front Osaka Clinic Gynecology

komiya520@ivfjapan.com+81-(0)6-6377-8824

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026