Oral versus vaginal administration of misoprostol for induction of labor in women with pre labour rupture of membranes. Results of a randomized controlled trial

Oral versus vaginal administration of misoprostol for induction of labor in women with pre labour rupture of membranes. Results of a randomized controlled trial - Oral versus vaginal misoprostol for PROM

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039212

Enrollment

Registered

2021-01-20

Start date

2019-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature rupture of membranes at term

Interventions

25 mcg of misoprostol 2- hourly, orally 25mcg misoprostol vaginally, 3-hourly

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: RROM

Exclusion criteria

Exclusion criteria: CD 4 BS 6

Design outcomes

Primary

Measure	Time frame
Primary outcome measure was to compare the effectiveness of orally administered misoprostol, with vaginally administered misoprostol for induction of labor in PROM cases.	—

Secondary

Measure	Time frame
Secondary outcomes were evaluation of mean interval between induction and active labor and the Induction to delivery interval.	—

Countries

Asia(except Japan)

Contacts

Public ContactRahul Bhargava

Rama Medical College Hapur

brahul2371@gmail.com9999055223

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026