Exploring radiosensitivity predictive factors using body fluid metabolomes for non-small cell lung cancer

Exploring radiosensitivity predictive factors using body fluid metabolomes for non-small cell lung cancer - Exploring radiosensitivity predictive factors using body fluid metabolomes for non-small cell lung cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000039209

Enrollment

Registered

2020-01-21

Start date

2020-01-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-small cell lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Twenty years of age or older; patients histologically diagnosed with non-small cell lung cancer (NSCLC), or diagnosed by the cancer board conference, in case where the histological diagnosis appears risky. 2)Patients suitable for curative radiotherapy 3)No history of thoracic radiotherapy

Exclusion criteria

Exclusion criteria: 1)Patients with active interstitial pneumonia 2)Patients with severe liver cirrhosis, diabetes mellitus or cardiovascular diseases 3) Patients with malignancies other than lung cancer

Design outcomes

Primary

Measure	Time frame
We collected patients' saliva metabolites before, 2 weeks after, and 3 months after the start of radiotherapy, and just after the end of treatment. To search for independent patient-related risk factors for predicting future radiation pneumonitis using saliva metabolomes.	—

Countries

Japan

Contacts

Public ContactSachika Shiraishi

Toyko Medical University Department of radiology

s-nogi@tokyo-med.ac.jp0333426111

Outcome results