asthma-COPD overlap
Conditions
Sponsors
Kansai Medical University Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: age over 40 years old Patients with asthma-COPD overlap as follow past history of episodic wheezeing bronchial hyperrectivity of 20% fall of FEV1 after inhalation of methacholine, or bronchial reversivirity of 12% and 200 ml improvement of FEV1 after inhalation of bronchodilator. Without cardiac asthma Under 70% of FEV1/FVC Under 80% of FEV1 after bronchodilator therapy Patients with asthma-COPD overlap diagnosed by treated by 250microg/10microg of Fluticasone propionate /Formoterol Outpatient with stable symptoms Agreement for the enrollment of this study
Exclusion criteria
Exclusion criteria: 1) Patients with unstable symptoms 2) Patients needed hospitalization because of infectious diseases 3) Patients with hospitalization within 8 weeks 4) Patients with severe hepatic or renal disease 5) Patients with uncontrolled diabes mellitus 6) Female with pregnancy 7) Female breast-feeding baby 8) Patients enrolled by clinical trials within 3 month 9) Patients recognized as insufficient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of forced expiriratory volume in one second, a respiratory function test. | — |
Countries
Japan
Contacts
Public ContactYoshihisa Ishiura
Kansai Medical University Medical Center Division of Respiratory, Oncology and Allergy
Outcome results
None listed