Factors influencing gait velocity improvement following botulinum toxin injection for plantar flexors spasticity in patients with stroke

Factors influencing gait velocity improvement following botulinum toxin injection for plantar flexors spasticity in patients with stroke - Factors influencing gait improvement after botulinum therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000039036

Enrollment

Registered

2019-12-31

Start date

2014-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

BoNT-A administration: 300 units BoNT-A administration: 300 units Physical therapy: 2 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Unilateral lesions in the cerebrum; 2. At least 6 months since stroke onset; 3. Walking ability at monitoring level or higher; 4.Spasticity of at least 1+ on the modified Ashworth scale in the ankle plantar flexor muscle.

Exclusion criteria

Exclusion criteria: 1. Higher brain dysfunction that presents problems for intervention and/or evaluation; 2. Cardiovascular disease that restricts exercise; 3. BoNT-A administration within the previous 4 months.

Design outcomes

Primary

Measure	Time frame
gait velocity, spasticity	—

Countries

Japan

Contacts

Public ContactKazuki Fujita

Fukui Health Science University Faculty of Health Science, Department of Rehabilitation

k.fujita@fukui-hsu.ac.jp0776-59-2200

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026