Heart failure
Conditions
Interventions
None listed
Sponsors
Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
Iwate Tohoku Medical Megabank Organization, Iwate Medical University Division of Cardiology, Department of Internal Medicine, Iwate Medical University Tohoku Medical Megabank Organization, Tohoku University Department of Diagnostic Imaging, Hokkaido University Graduate School of Medicine Laboratory of Media Dynamics, Graduate School of Information Science and Technology, Hokkaido University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: HF arm 1. 20 years of age or older 2. Patients who meet the diagnostic criteria for heart failure in the current heart failure guidelines (JCS 2017,ESC 2016) 3. Patients who give written informed consent AF arm 1. 20 years of age or older 2. Left ventricular ejection fraction of 40% or more 3. NYHA functional class 1 4. Patients who give written informed consent Control 1. Participants in the Tohoku Medical Megabank Project 2. 20 years of age or older at the time of informed consent.
Exclusion criteria
Exclusion criteria: HF arm 1. Sepsis 2. Acute coronary syndrome 3. Acute myocarditis 4. Patients who received heart transplantation or can be candidate for heart transplantation (i.e., patients with left ventricular assist device for waiting heart transplantation) 5. Scheduled for open heart surgery within a month 6. Patients who are considered as inappropriate candidate for this study by the principal investigator AF arm 1. Patients with a history of hospitalization for heart failure 2. Acute coronary symdrome 3. Patients who are considered as inappropriate candidate for this study by the principal investigator Control 1. Diagnosed as atrial fibrillation 2. Diagnosed as heart failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause death Re-admission due to worsening heart failure More than 10% additional reduction on Left ventricular ejection fraction | — |
Secondary
| Measure | Time frame |
|---|---|
| Implantation of ventricular assist device Heart transplantation New-onset atrial fibrillation Stroke Systemic embolism Acute myocardial infarction Hospitalization due to major bleeding Ventricular arrhythmia | — |
Countries
Japan
Contacts
Public ContactToshiyuki Nagai
Faculty of Medicine and Graduate School of Medicine, Hokkaido University Department of Cardiovascular Medicine
Outcome results
None listed