Comparison of postoperative liver function between total intravenous anesthesia and inhalation anesthesia in patients with preoperatively elevated liver transaminase levels: a single-center retrospective cohort study

Comparison of postoperative liver function between total intravenous anesthesia and inhalation anesthesia in patients with preoperatively elevated liver transaminase levels: a single-center retrospective cohort study - Effects of TIVA versus inhalation anesthesia on elevated LFT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000038949

Enrollment

626

Registered

2019-12-21

Start date

2018-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with preoperatively elevated liver transaminase levels who underwent surgery under general anesthesiaanesthesia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients that featured elevated preoperative liver enzymes (AST > 40 U/L or ALT > 40 U/L) within 24 hour before operation in non-hepatic surgeries

Exclusion criteria

Exclusion criteria: patients with normal range of preoperative LFT results, hepatic surgery,heart surgery and Cesarean section

Design outcomes

Primary

Measure	Time frame
The changes (%, increase or decrease) in liver enzyme (ALT) levels measured within 24 hours before and after surgery	—

Secondary

Measure	Time frame
30-day mortality, length of postoperative hospital stay	—

Countries

Asia(except Japan)

Contacts

Public ContactSeok Kyeong Oh

Korea University Guro Hospital Seoul

nanprayboy@korea.ac.kr82-2-2626-1437

Outcome results