Idiopathic Pulmonary Fibrosis
Conditions
Interventions
Arm A A symptom-limited incremental exercise tests were carried out on cycle-ergometer with ambient air. Next time, patient performed constant-load symptom-limited exercise test in a random order arm
Sponsors
Kobe City Medical Center General Hospital Department of Rehabilitation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patient aged =<40 years at informed consent 2. Patient with idiopathic pulmonary fibrosis diagnosed according to the diagnostic criteria of INPULSIS trial and 2011 or 2018 ATS/ERS/JRS/ALAT guideline 3. Patients who have exercise induced oxygen desaturation (SpO2 <90%) during 6 minute walking test on ambient air 4. Patient with dyspnea on exercise (1 =< mMRC =< 3) 5. Stable patients without any infection nor acute exacerbation within 3 months 6. Patients who can see a doctor's visit to take outpatient rehabilitation program 7. Patients who can adequately answer the questionnaire about subjective symptom 8. Written informed consent is obtained
Exclusion criteria
Exclusion criteria: 1. Patients with connective tissue disease, neuromuscular disease or orthopedic problem and other disease which may affect to exercise assessment and requires exercise limitation 2. Patients who have pulmonary hypertension, according to WHO guideline [I-II => NYHA and 25mmHg => mean pulmonary arterial pressure (40mmHg => TRPG)] and use a pulmonary vasodilator 3. Using an anti-arrhythmic drug 4. Using long-term oxygen therapy 5. Patients who cannot be evaluated by 6 minute walk test for any reason 6. Patients who are judged by the investigator as not adequate to participate in this study 7. History of malignant disease within 3 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endurance time of exercise | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Dyspnea (modified Borg Scale) 2. Fatigue of lower limb (modified Borg Scale) 3. Desaturation (SpO2) 4. Heart rate 5. Blood pressure 6. Patient comfort to each device (Visual Analog Scale) | — |
Countries
Japan
Contacts
Public ContactJumpei Harada
Kobe City Medical Center General Hospital Department of Rehabilitation
Outcome results
None listed