A clinical study on the change of muscle strength, muscle mass, physical performances, and other parameters in perioperative esophageal cancer patients

A clinical study on the change of muscle strength, muscle mass, physical performances, and other parameters in perioperative esophageal cancer patients: a multicenter, single arm, prospective observational study - A clinical study on the change of muscle strength, muscle mass, physical performances, and other parameters in perioperative esophageal cancer patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000038794

Enrollment

Registered

2019-12-06

Start date

2019-12-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients who are scheduled to undergo esophagectomy (2) Patients of 20 years or older at the time of informed consent (3) Patients who can provide written informed consent

Exclusion criteria

Exclusion criteria: (1) Patients with the Performance Status on the Eastern Cooperative Oncology Group of 3 or greater (2) Patients with severe complications such as poorly-controlled diabetes, hypertension, etc. (3) Patients with muscular diseases including active myopathy or muscular dystrophy (4) Patients who have history of lower limb fractures within 6 months before the day of informed consent (5) Patients who cannot keep standing or sitting, walk, and etc. due to severe disabilities or diseases (e.g., stroke with hemiparesis, myasthenia gravis, Parkinson's disease, peripheral neuropathy, intermittent claudication due to advanced peripheral vascular disease with poorly-controlled pain, spinal stenosis, or severe osteoarthritis of the knee or hip, and others) (6) Patients who cannot continue deep breathing due to respiratory diseases (7) Patients with chronic obstructive pulmonary disease whose severity grade is 3 or greater on the modified medical research council dyspnea scale (The 5th JRS Guidelines for the Management of Chronic Obstructive Pulmonary Disease) (8) Pregnant and breastfeeding patients (9) Patients who are participated in a clinical trial or clinical study and received an unapproved drug within 16 weeks before the day of informed consent (10) Patients who are deemed unsuitable for inclusion in this study for any other reason based on assessment by the investigator or sub-investigator

Design outcomes

Primary

Measure	Time frame
muscle strength, muscle mass, physical performances, respiratory functions, ADL, and body weight	—

Countries

Japan

Contacts

Public ContactRyo Ogawa

Nagoya city university graduate school of medical sciences Gastroenterological surgery

r-ogawa@med.nagoya-cu.ac.jp052-853-8226

Outcome results