Usefulness of serum HBV RNA as possible marker for HBV persistent infection and reactivation

Usefulness of serum HBV RNA as possible marker for HBV persistent infection and reactivation - Clinical significance of serum HBV RNA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000038790

Enrollment

200

Registered

2019-12-05

Start date

2019-12-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic hepatitis B, Acute hepatitis B, HBV cirrhosis, HBV carrier, past history of HBV infection

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients of chronic hepatitis B, acute hepatitis B, HBV carrier, past history of HBV infection, especially those who are undergoing immunosuppression or chemotherapy in Keio University Hospital.

Exclusion criteria

Exclusion criteria: Patients who refuse to participate or who are deemed inappropriate to participate

Design outcomes

Primary

Measure	Time frame
The correlation of serum HBV RNA with 1. Serum HBV DNA 2. Serum HBsAg 3. Serum HBcrAg at inclusion, before treatment, and 1-12 months after inclusion/ treatment	—

Secondary

Measure	Time frame
1. Serum AST, ALT 2. Liver residual function including serum bilirubin, albumin, PT activity 3. Liver fibrosis serological markers 4. Incidence of de novo or recurrent HCC	—

Countries

Japan

Contacts

Public ContactPo-sung Chu

Keio University Gastroenterology and Hepatology, Internal Medicine, School of Medicine

pschu0928@iCloud.com03-5363-3790

Outcome results