Effect of combined topical application of cosmetic gel and emulsion on skin biophysical characteristics: a randomized single-blind trial

Effect of combined topical application of cosmetic gel and emulsion on skin biophysical characteristics: a randomized single-blind trial - Effect of combined topical application of cosmetic gel and emulsion on skin biophysical characteristics: a randomized single-blind trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000038756

Enrollment

Registered

2020-01-10

Start date

2019-12-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy person

Interventions

For 8 weeks, application of cosmetic gel plus emulsion to which one side of face and only emulsion to which the other side

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1.More than 30 years old and under 60 when obtaining consent 2.Feel dry for skin 3.Person who is judged to be medically normal by investigator and subinvestigators based on results of examination before application of cosmetic

Exclusion criteria

Exclusion criteria: 1.Habitually apply topical preparation, medicine and supplement likely affecting test sites (cosmetic for skin whitening, oral contraceptives etc.) when obtaining consent 2.Atopic dermatitis 3.Deeply suntanned when obtaining consent 4.Difference more than twice water content value between test sites (both cheeks)in screening 5.Person with past surgical history on test sites 6.History of allergy or oversensitivity when applies medicine and cosmetic 7.Smoker including person who has stopped smoking within 60 days prior to consent date 8.Not expected to follow the rules determined in this study 9.Person who has enrolled in other clinical study 10.Pregnant, with likelihood for pregnancy, planning for pregnancy , Breastfeeding 11.Take hormone replacement therapy 12.Person who is judged to be inappropriate by investigator and subinvestigators

Design outcomes

Primary

Measure	Time frame
Evaluation of skin biophysical characteristics (stratum corneum hydration, viscoelasticity, skin color, pigmented spots, corneocyte surface area)	—

Countries

Japan

Contacts

Public ContactAkihiro Aoki

Otsuka Pharmaceutical Co., Ltd. Otsu Skin Care Research Institute

aoki.akihiro@otsuka.jp077-521-8835

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026