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The Effect of Nasal Canula prior to Tracheal Intubation on Preventing Hypoxemia in Neonate and Infant : a Double-blind,Randomised Controlled Trial

The Effect of Nasal Canula prior to Tracheal Intubation on Preventing Hypoxemia in Neonate and Infant : a Double-blind,Randomised Controlled Trial - Apneic Oxyganation by Nasal Canula in Neonate and Infant

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000038733
Enrollment
240
Registered
2019-12-02
Start date
2019-12-02
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonate and infant who require intubation under general anesthesia

Interventions

After the induction of general anesthesia, we will attach an atom nasal cannula to all patients but administer oxygen to control group patients (group 1). We provide patient ventilation with 100% FiO

Sponsors

Saitama Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Men and women who have general anesthesia at our hospital for 0 months or more and less than 24 months. 2) Patients with ASA-PS1 or 2. 3) When the patient's representative shows sufficient understanding and consents to participate.

Exclusion criteria

Exclusion criteria: Rapid sequence induction Emergency case Predicted difficult airways Differential lung ventilation Heart and cardiovascular disease Congenital heart disease and respiratory disease

Design outcomes

Primary

MeasureTime frame
Time from the start of intubation until SpO2 drops to 95%.

Secondary

MeasureTime frame
1)Time and SpO2 from the start of intubation to the end of the first or second intubation. Time and SpO2 until the re-mask ventilation. 2)SpO2 every 15 seconds from intubation start to completion. 3)Extract cases that required time for intubation and compare the lowest SpO2 by group. 4)Incidence of complications from oxygen administration from nasal cannula.

Countries

Japan

Contacts

Public ContactSachi Ishida

Saitama Children's Medical Center Anesthesiology

sishida-bb@umin.ac.jp048-601-2200

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026