gastric cancer
Conditions
Interventions
Control group: The patient is placed under epidural anesthesia during surgery, and epidural anesthesia is used for postoperative analgesia.
Intervention group: Wound local anesthesia is performed
Sponsors
NPO Digestive Disease Support Organization (DDSO)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Histologically proven adenocarcinoma of the stomach 2) Surgically resectable tumor (cStageI-III) by laparoscopic gastrectomy 3) Age 20 > years 4) ECOG performance status 0 or 1. 5) Cases with adequately maintained organ functions and fullfilling the following conditions within 4 weeks before registration. WBC>3000 Plt>100000 AST<100 ALT<100 Total bilrbin<2.0mg/dL Serum creatinine<1.5mg/dL 6) Written informed consent
Exclusion criteria
Exclusion criteria: 1) Patients with synchronous or metachronous malignancies. 2) Inappropriate for epidural anesthesia 3) Patients with Hugh-Jones II or higher pulmonary disease 4) Unstable angina pectoris or history of myocardial infarction within 6 months. 5) Uncontrollable hypertension. 6) Uncontrollable diabetes mellitus 7) History of hypersensitivity of acetaminophen 8) History of hypersensitivity of ropivacaine hydrochloride hydrate or lidocaine hydrochloride 9) History of hypersensitivity of aspirin-induced asthma 10) Continuous systemic steroid therapy. 11) Women during pregnancy or breast feeding. 12) Judged inappropriate by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients with an NRS score of 4 or higher at 24 hours postoperatively. | — |
Countries
Japan
Contacts
Public ContactJun Kinoshita
Kanazawa University Gastroenterologic Surgery
Outcome results
None listed