Treatment mechanism of anhedonia by repetitive Transcranial Magnetic Stimulation in major depressive disorder: analysis using rs-fMRI

Treatment mechanism of anhedonia by repetitive Transcranial Magnetic Stimulation in major depressive disorder: analysis using rs-fMRI - Treatment mechanism of anhedonia by repetitive Transcranial Magnetic Stimulation in major depressive disorder

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000038578

Enrollment

Registered

2019-11-14

Start date

2019-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

major depressive disorder

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) participation in a research "effect of rTMS on cognitive function in depressive episode" which is main protocol of this study. 2) those who can read and understand infromed consent form of this study. 3) major depressive disroder according to Diagnostic and Statistical Manual of Mental Disorders. 4) those who are 20-75 years old

Exclusion criteria

Exclusion criteria: 1) those who have a history of psychotic episode, obsessive compulsive disorder, post traumatic stress disorder and/or eating disorder. 2) those who have a history of electro-convulsive therapy, rTMS, vagus nerve stimulation, deep brain stimulation and/or transcranial direct current stimulation. 3) those who are pregnant. 4) those who have a history of a episode of convulsion by epilepsy and have relatives with epilepsy.

Design outcomes

Primary

Measure	Time frame
change in inter-regional functional connectivity of salience network by rTMS	—

Countries

Japan

Contacts

Public ContactFumitoshi Kodaka

The Jikei University School of Medicine Department of Psychiatry

kodaka@jikei.ac.jp+81-3-3433-1111

Outcome results