None (Healthy adults)
Conditions
Interventions
Microorganism containing food (tablet form), once a day for 12 weeks
Microorganism not containing food (tablet form), once a day for 12 weeks
Sponsors
University of Malaya
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Provide signed and dated informed consent form (2) Willingness to comply with all study procedures for the duration of the study (3) Malaysia citizen (4) Aged more than 18 years old (adult) (5) Residing at specific communities (6) Not feeling sick with fever for the past 2 weeks in the preliminary screening (7) No underlying diseases or sickness in the preliminary screening (8) Individuals tested negative for anti-virus antibodies in the preliminary blood test
Exclusion criteria
Exclusion criteria: (1) Unable to provide signed and dated informed consent form (2) Unable to comply with all the study procedures (3) Below legal age (aged < 18 years old) (4) Unable to identify biological gender (5) Not Malaysian citizen (6) Allergic to fermented food products (7) Take steroid regularly (e.g. for allergies) (8) Consume foods, drinks or supplements containing probiotic on regular basis (9) Women who are pregnant, or intend to get pregnant during the study period, or breastfeeding mothers (10) Planned to go overseas for more than two weeks in total all over the study time. (11) Participate in other tests with the intake of food and pharmaceutical products (12) With the history suffering from digestive diseases or operation experience of the digestive tracts to affect the digestion and absorption (13) Are positive for specific anti-viral antibodies or viral antigens (HBV, HCV, HIV, or HTLV-1) in inspection of the pre-intervention blood sample (14) Cannot stop drinking alcohol for two days before drawing blood (15) Persons determined as not appropriate based on the blood biochemistry test results (16) Additionally, other persons whom the principal investigator or sub-investigator deems inappropriate as participants for the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Incident rate of specific infectious diseases - Severity of symptoms of specific infectious diseases - Antibody titers against specific virus in blood | — |
Secondary
| Measure | Time frame |
|---|---|
| - Specific virus titers in blood - Incident rate of ful-like illness - Severity of symptoms of ful-like illness | — |
Countries
Asia(except Japan)
Contacts
Public ContactKhor Chee Sieng
University of Malaya Tropical Infectious Diseases Research and Education Center
Outcome results
None listed