Study on the relationship between gum chewing during perioperative period and tangue pressure in esophageal cancer patients

Study on the relationship between gum chewing during perioperative period and tangue pressure in esophageal cancer patients - Study on the relationship between gum chewing during perioperative period and tangue pressure in esophageal cancer patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000038361

Enrollment

Registered

2020-04-01

Start date

2021-03-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Gum chewing training during perioperative period in the patients with esophageal cancer

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients who undergo thoracic esophageal cancer surgery at our hospital 1) The patients who will undergo primary radical operation 2) The Patients who have received sufficient explanation for participation in this study, and who have received sufficient written consent from the patient himself / herself with sufficient understanding

Exclusion criteria

Exclusion criteria: 1)The patients who cannot gum chewing because of denture or something 2) The Patients who are determined to be inappropriate as research subjects by the principal investigator or other investigators

Design outcomes

Primary

Measure	Time frame
The ratio of the patients whose tongue pressure was decreased the day after 2 weeks of surgery	—

Secondary

Measure	Time frame
The following data will be evaluated on 1) The starting day of gum chewing, 2) The day before surgery, 3) The day after 2 weeks of surgery. -Swallowing function: tongue pressure, RSST, presence/absence of recurrent laryngeal nerve palsy, oral diadocokinesis -Masticatory function: Masticatory ability, occlusal force -Oral hygiene: degree of tongue coating, total number of bacteria on back of tongue, bacterial flora -Mouth dryness: Oral moisture meter measurement value -Equilibrium function: Opening one leg up time The following data will be evaluated on the period between the starting day of gum chewing and the day of end of observational period -Adverse events, safety: Postoperative complications such as suture failure, accidents due to gum mastication (detachment of prostheses and restorations, temporomandibular joint pain, etc.), and other adverse events -Postoperative lung complications (JCOG postoperative complication criteria (Clavien-Dindo classification)) v2.0 -Nutrition related items: Oral intake start time, discharge time, ratio of oral intake to total nutrition intake, ratio of home discharge and hospital transfer, etc. -Postoperative delirium: Contents of medical records	—

Measure

Time frame

The following data will be evaluated on 1) The starting day of gum chewing, 2) The day before surgery, 3) The day after 2 weeks of surgery. -Swallowing function: tongue pressure, RSST, presence/absence of recurrent laryngeal nerve palsy, oral diadocokinesis -Masticatory function: Masticatory ability, occlusal force -Oral hygiene: degree of tongue coating, total number of bacteria on back of tongue, bacterial flora -Mouth dryness: Oral moisture meter measurement value -Equilibrium function: Opening one leg up time The following data will be evaluated on the period between the starting day of gum chewing and the day of end of observational period -Adverse events, safety: Postoperative complications such as suture failure, accidents due to gum mastication (detachment of prostheses and restorations, temporomandibular joint pain, etc.), and other adverse events -Postoperative lung complications (JCOG postoperative complication criteria (Clavien-Dindo classification)) v2.0 -Nutrition related items: Oral intake start time, discharge time, ratio of oral intake to total nutrition intake, ratio of home discharge and hospital transfer, etc. -Postoperative delirium: Contents of medical records

—

Countries

Japan

Contacts

Public ContactReiko Yamanaka

Okayama University hospital Hospital Dentistry

reiko_y@md.okayama-u.ac.jp81862356588

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026