Evaluation of titin N-fragment in urine as a marker of muscle catabolism in intensive care

Evaluation of titin N-fragment in urine as a marker of muscle catabolism in intensive care - Evaluation of titin N-fragment in urine as a marker of muscle catabolism in intensive care

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000038353

Enrollment

Registered

2019-10-21

Start date

2019-10-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post intensive care syndrome

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ICU admission patients over 20 years old Patients expected to be hospitalized for 10 days or longer Patients who have obtained consent from the person or a representative

Exclusion criteria

Exclusion criteria: Pregnant women Under 35 years old or women who can get pregnant Patients without self urine Patients who have difficulty measuring thigh muscle mass after trauma or amputation ECMO patients Other patients who are determined to be inappropriate as subjects by the principal investigator

Design outcomes

Primary

Measure	Time frame
correlation between titin fragment in urine and femoral muscle mass change in 10 days evaluated by CT	—

Secondary

Measure	Time frame
correlation between titin fragment in urine and SOFA score, inflammation marker, calorie intake or protein intake	—

Countries

Japan

Contacts

Public ContactHidehiko Nakano

Hitachi General Hospital Department of Emergency and Critical Care Medicine, Hitachi General Hospital

be.rann1988jp@gmail.com0294-23-1111

Outcome results