Healthy infants
Conditions
Interventions
Ingestion of probiotics to healthy infants from registration to 3 month s after birth.
Ingestion of placebo to healthy infants from registration to 3 month s after birth.
Sponsors
Matsumoto City Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) healthy full-term infants within 7 days after birth 2) full-term (37 weeks <= gestational age < 42 weeks) infants 3) Infants with informed consent by representative family 4) Infants considered healthy by the investigators
Exclusion criteria
Exclusion criteria: 1) Multiple-birth infants 2) Infants with small or large birth-weight for gestational age 3) Infants with any severe congenital disease in blood, liver, heart, kidney, gastro-intestine and so on or who are suspected with immune disorder 4) Infants whose mother has a serious disorder in liver, kidney, heart, blood, lung, endocrine system or metabolic system so on, or mental disorders 5) Infants who were administrated with probiotics or antibiotics 6) Infants who are planned to use probiotics other than the study supplement during the study 7) Infants considered to be unsuitable for enrollment by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Colonization of bifidobacteria | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Intestinal environment 2. Biochemical measurements of stools 3. Defecation frequency and fecal condition 4. Health condition | — |
Countries
Japan
Contacts
Public ContactRyuji Tsuno
Matsumoto City Hospital Pediatrics
Outcome results
None listed