Healthy volunteer
Conditions
Interventions
Ingestion of supplement-1 for 12 consecutive weeks.
Ingestion of supplement-2 for 12 consecutive weeks.
Ingestion of placebo for 12 consecutive weeks.
Sponsors
Pharma Foods International Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Subjects who are adult male and female with subjective symptoms of knee joint pain. 2. Subjects who are classified into 0-I grade on the basis of the Kellgren-Lawrence classification (Subjects who undiagnosed with knee osteoarthritis by doctor). 3. Subjects who have agreed to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Subjects with a history of treatment of malignant tumor, heart failure, myocardial infarction. 2. Subjects receiving treatment for the following chronic diseases, atrial fibrillation, arrhythmia, liver disorder, kidney disorder, cerebrovascular disorder, rheumatism, diabetes, dyslipidemia, hypertension, knee joint disease, other chronic diseases. 3. Subjects who routinely use medicines (including herbal medicine). 4. Subjects who are taking action to improve knee joint pain (including going to the hospital and treatment), and using medicines and health foods. 5. Subjects with allergies (medicine / test food related food). 6. Subjects who are planning to become pregnant or lactating. 7. Subjects who are judged as unsuitable for the study by doctor for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| JKOM, JOA | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee joint subjective symptoms (VAS) Blood test (CTx-II, C2C, PIIANP) | — |
Countries
Japan
Contacts
Public ContactMaya Sakashita
Pharma Foods International Co., Ltd. Research and Development Department
Outcome results
None listed