Clinical study for severity of neonatal hypoxic-ischemic encephalopathy

Cohort-study of a novel biomarker for neonatal hypoxic-ischemic encephalopathy - Multicenter cohort-study for neonatal hypoxic-ischemic encephalopathy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000038267

Enrollment

120

Registered

2019-10-15

Start date

2018-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal hypoxic-ischemic encephalopathy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with neonatal hypoxic-ischemic encephalopathy. 1) acidemia (less than 7 of pH or more than 16 of base excess), derived with umbilical or autologous artery. 2) perinatal emergency events (ex. premature separation) and severe asphyxia. 1) or 2). 2. Control. neonates without hypoxic-ischemic encephalopathy.

Exclusion criteria

Exclusion criteria: 1. Patients with neonatal hypoxic-ischemic encephalopathy, accompanied with anomalies, brain malformation, genetic diseases, metabolic disorders and congenital infections. 2. Controls, accompanied with anomalies, brain malformation, genetic diseases, metabolic disorders and congenital infections.

Design outcomes

Primary

Measure	Time frame
sLOX-1 cut-off value for severity of neonatal hypoxic-ischemic encephalopathy	—

Countries

Japan

Contacts

Public ContactMasayuki Itoh

National Center of Neurology and Psychiatry Biochemistry and Cellular Biology

itoh@ncnp.go.jp042-341-2712-5823

Outcome results