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Is exercise for nephrotic syndrome safe and effective?

Verification of safety and efficacy of early exercise therapy intervention for acute nephrotic syndrome - Nephrotic syndrome test

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000038250
Enrollment
25
Registered
2019-10-10
Start date
2019-10-20
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephrotic syndrome

Interventions

&lt
Rehabilitation started 11 days after treatment or renal biopsy. Start exercise therapy immediately after rehabilitation. *Exercise therapy Conduct muscular strength training and endurance trainin
Rehabilitation started 11 days after treatment or renal biopsy. Perform light load exercise immediately after rehabilitation. Start exercise therapy 4 weeks after starting rehabilitation.

Sponsors

Hamamatsu University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients admitted to our hospital with nephrotic syndrome and starting or increasing steroid therapy. (Minimal change nephrotic syndrome, membranous nephropathy, focal segmental glomerulosclerosis, membranoproliferative glomerulonephritis, lupus nephritis) 2.ADL is independent

Exclusion criteria

Exclusion criteria: 1.A person with a history of comorbid heart disease or pulmonary disease. 2.Those who cannot perform tests such as muscle strength measurement or appropriate exercise therapy due to orthopedic disease. 3.Those with unhealed cancer

Design outcomes

Primary

MeasureTime frame
Exercise tolerance(Before treatment,4 weeks after starting rehabilitation,8 weeks after starting rehabilitation)

Secondary

MeasureTime frame
Isometric knee extension muscle strength Skeletal muscle mass Walking speed Grip strength Depression(CES-D scale) Quality of life(SF-36) Nephrotic syndrome-related marker Renal function Presence of anemia Thrombosis related markers

Countries

Japan

Contacts

Public ContactYuma Hirano

Hamamatsu University Hospital Department of Rehabilitation

yuma.h.pt@gmail.com053-435-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Aug 14, 2026