Healthy Adults
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Subjects who gave written informed consent to participate in the study. 2) Individuals who are diagnosed as having no health problems based on a physician's interview 3) Men and women aged 20-65 years at the time of informed consent 4) Non-smokers for at least 1 year 5) Persons who have not undergone dental treatment or cleaning by a dentist within 6 months retrospectively from the date of the screening examination. 7) Those who have 24 or more teeth left behind.
Exclusion criteria
Exclusion criteria: 1) Pregnant women or women of childbearing potential, and women who wish to become pregnant during the study period 2) Lactating women 3) Persons with a history of serious disease (including Sjoegren's syndrome) 4) Patients with a history of hypersensitivity to gelatin or sugar alcohol 5) Persons who may require dental treatment (including orthodontic treatment) during the study participation period. 6) Extraction of wisdom teeth or treatment of tooth extraction other than tooth extraction for convenience in orthodontic treatment 7) Patients who have taken antibiotics (antibiotics/antibiotics) within 3 months 8) Persons who may use antihistamines (e.g., due to pollinosis or allergy) during the study period (survey the use of antihistamines and cold remedies in advance questionnaires or diaries). 9) Other persons who the investigator or the investigator judges to be inappropriate as subjects of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding on Probing | — |
Secondary
| Measure | Time frame |
|---|---|
| PPD CAL P1I GI | — |
Countries
Japan
Contacts
Medical Corporation Chiseikai Tokyo Center Clinic Clinical Research Center