Appendicitis
Conditions
Interventions
In all the patients, general anesthesia is induced using inhaled sevoflurane in an air-oxygen mixture, including 2mcg/kg fentanyl and 0.6 mg/kg rocuronium, followed by tracheal intubation. The nerve
Sponsors
Tokyo Metropolitan Children Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Children between the ages of 7 and 17 years undergoing laparoscopic appendectomy with American Society of Anesthesiologists (ASA) physical status of 1 or 2 are enrolled. The child's parent or legal guardian is provided oral and written informed consent. Assent to participate in the study is also given by children.
Exclusion criteria
Exclusion criteria: American Society of Anesthesiologists (ASA) physical status of 3 or higher Allergy of local anesthetics Anatomical abnormalities at the site of the nerve block History of abdominal surgery Preoperative analgesic administration Neurological abnormalities at the site of the nerve block Severe heart and/or renal failure (EF<40, Cre>1.0) Coagulopathy Additional procedures planned via a separate incision at the time of the laparoscopic appendectomy Contraindications for any of the medications described in the protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The maximum NRS score in 3 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| The need for rescue analgesia, Face Scale, NRS score, the number of anesthetised dermatomes, and complications related to the use of local anesthetic in 48 hours postoperatively The pharmacokinetic profile of levobupivacaine after nerve block for 2 hours | — |
Countries
Japan
Contacts
Public ContactMakoto Sato
Tokyo Metropolitan Children Medical Center Department of Anesthesiology
Outcome results
None listed